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No, there is no specific scientific evidence which suggests that regular use of anabolic steroids can lead to ulcerative colitis, but anecdotal reports in athletes are very encouraging and encouraging for me to research further.
My first question is – Are there any studies which show that regular steroid use does lead to ulcerative colitis in animals?
I would also like to make a couple of observations.
First and foremost, I would not argue against the notion that there is a causal relationship between regular steroid use and ulcerative colitis. There is no doubt on the issue.
However, I would not argue that this relationship cannot be causal in certain circumstances either. For example, it is very well documented that individuals with anabolic steroid use syndrome also suffer from non-ulcerative colitis and other inflammatory bowel disorders. I also know of at least one individual with inflammatory bowel disease for whom steroid use caused ulcerative colitis in both mucosa and colon. Furthermore, evidence indicates that regular steroid use results in mucosal atrophy, leading to alterations in the barrier function of the gut, and with it the development of mucosal inflammatory bowel disease which also occurs with anabolic steroid use. I wouldn’t be surprised if the gut tissue of an individual with anabolic steroid use syndrome also became dysbiotic.
For this reason I think it would be useful if anabolic steroid users were tested regularly for inflammatory bowel disease. The evidence for this is not conclusive with the small sample sizes that I have seen but some researchers are using the most up-to-date methods to attempt to find such a link. As for a causal relationship between anabolic steroid use and ulcerative colitis and other inflammatory bowel disease, the available evidence simply does not support this.
In short, I do not believe that any causal relationship exists. I think that at some point there may have been some connection but the question has gone silent and there is currently no real evidence.
Do you think that regular use of anabolic steroids can lead to ulcerative colitis, or at the very least contribute to ulcerative colitis.
I believe that a causal relationship between regular steroid use and ulcerative colitis has not been established. However, we need to learn more about this topic and I will be exploring it with research partners in different countries. This is a very important topic and I would love to find out more about it. If there is any evidence that regular steroid use can lead to ulcerative colitis and possibly other inflammatory bowel diseases, I will be looking at more studies.
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