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For those men without a prostate cancer diagnosis, there was not any consistent evidence for an increased risk for prostate cancer mortality, even though a statistically significant adjusted OR for prostate cancer mortality was observed for all age groups. For men diagnosed with prostate cancer, the age-adjusted OR of prostate cancer mortality was 3. CONCLUSIONS: This report highlights recent findings regarding an increased risk for prostate cancer mortality in those men who have no risk for cardiovascular disease. Although our findings also suggest that testosterone and prostaglandins may play roles in prostate cancer, the effect of androgens on prostate cancer risk is not clear. It is also important to note that men with BPH are at increased risk for prostate cancer and may experience the adverse effects of androgens, while men whose BPH is benign, but whose testosterone levels are high, have a lower risk for prostate cancer, possibly due to lower androgen exposure, .
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